TABLE 3.

Correlations between CALD1 and immune cells markers.

Description	Gene marker	GSE39582		GSE41258
		Cor	P	Cor	P
CD8+ T cell	CD8A	0.072	0.313	0.143	0.199
	CD8B	−0.104	0.143	NA	NA
T cell (general)	CD3D	−0.017	0.816	0.134	0.231
	CD3E	−0.058	0.413	−0.036	0.745
	CD2	0.162	*	0.207	0.063
B cell	CD19	−0.025	0.727	0.053	0.634
	CD79A	−0.081	0.253	0.185	0.097
Monocyte	CD86	0.537	***	−0.132	0.236
	CD115	0.586	***	0.585	***
TAM	CCL2	0.630	***	0.681	***
	IL10	0.272	**	0.087	0.436
M1 Macrophage	NOS2	−0.338	***	−0.499	***
	IRF5	−0.033	0.645	−0.051	0.646
	PTGS2	0.246	**	0.252	*
M2 Macrophage	CD163	0.564	***	0.474	***
	VSIG4	0.521	***	0.459	***
	MS4A4A	0.529	***	0.573	***
Neutrophils	CEACAM8	−0.145	*	−0.364	**
	ITGAM	0.640	***	0.577	***
	CCR7	−0.035	0.618	0.115	0.305
Natural killer cell	KIR2DL1	−0.266	**	−0.037	0.740
	KIR2DL3	−0.254	**	−0.270	*
	KIR2DL4	−0.199	**	−0.038	0.737
	KIR3DL1	0.066	0.355	0.371	**
	KIR3DL3	−0.279	***	−0.040	0.721
Dendritic cell	HLA-DPB1	0.486	***	NA	NA
	HLA-DQB1	0.352	***	NA	NA
	HLA-DRA	0.422	***	NA	NA
	HLA-DPA1	0.385	***	NA	NA
	CD1C	0.094	0.187	−0.236	*
	NRP1	0.754	***	0.742	***
	ITGAX	0.421	***	0.312	**
Th1	TBX21	−0.032	0.654	−0.086	0.444
	STAT4	0.297	***	−0.279	*
	STAT1	0.406	***	0.281	*
	IFNG	0.047	0.511	−0.308	**
	TNF	0.073	0.301	−0.307	**
Th2	GATA3	0.315	***	−0.031	0.784
	STAT6	−0.210	**	0.070	0.534
	STAT5A	0.042	0.558	0.124	0.265
	IL13	−0.215	**	−0.219	*
Tfh	BCL6	0.585	***	0.705	***
	IL21	0.074	0.295	−0.272	*
Th17	STAT3	0.034	0.633	−0.002	0.984
	IL17A	−0.067	0.349	−0.370	**
Treg	FOXP3	−0.094	0.185	−0.400	**
	CCR8	−0.076	0.282	−0.132	0.236
	STAT5B	0.264	**	0.268	*
	TGFB1	0.598	***	0.502	***
T cell exhaustion	PDCD1	−0.270	**	−0.303	**
	CTLA4	−0.319	***	−0.135	0.226
	HAVCR2	0.390	***	NA	NA
	GZMB	−0.016	0.826	0.033	0.766

*p < 0.05; **p < 0.01; ***p < 0.0001. Cor, Pearson’s correlation value; TAM, tumor-associated macrophage; Th, T helper cell; Tfh, follicular helper T cell; Treg, regulatory T cell; NA, not available.