Figure 2.

Differences in bacterial communities of biliary and duodenal microbiota of patients with choledocholithiasis. (A) Spearman correlation coefficients between biliary and duodenal samples in each patient. (B) Differences of microbial alpha-diversity between biliary microbiota and duodenal microbiota. Alpha-diversity was visualized by analysis of Box plots of ACE, chao1, Shannon, Simpson, and observed species index. (C) Differences of microbial beta-diversity between biliary and duodenal microbiota in patients. Beta-diversity was visualized by analysis of principal coordinates using weighted Unifrac distances. (D) LEfSe cladogram and LDA scores of differential features between biliary and duodenal microbiota.