Table 2.
Univariate Cox regression analyses for identifying clinicopathological parameters related to EC patients’ OS.
| Clinical feature | Univariate analysis | ||
|---|---|---|---|
| HR | 95%CI of HR | P value | |
| Risk High | 7.16 | 4.67-10.99 | <0.001 |
| Age, y | 1.03 | 1.01-1.05 | 0.002 |
| Race | |||
| Black | 1 (reference) | ||
| White | 0.95 | 0.56-1.60 | 0.835 |
| Other | 0.65 | 0.24-1.74 | 0.388 |
| AJCC stage | |||
| I | 1 (reference) | ||
| II | 1.91 | 0.88-4.15 | 0.104 |
| III | 3.27 | 1.99-5.37 | <0.001 |
| IV | 9.30 | 5.12-16.90 | <0.001 |
| Grade | |||
| Low | 1 (reference) | ||
| High | 3.19 | 1.85-5.49 | <0.001 |
| Margin_status | |||
| R0 | 1 (reference) | ||
| R1 | 1.95 | 0.78-4.91 | 0.156 |
| R2 | 6.62 | 3.43-12.78 | <0.001 |
| Surgical_approach | |||
| Minimally Invasive | 1 (reference) | ||
| Open | 0.78 | 0.50-1.21 | 0.274 |
| TCGA molecular classification | |||
| CN_HIGH | 1 (reference) | ||
| CN_LOW | 0.26 | 0.14-0.50 | <0.001 |
| MSI | 0.39 | 0.23-0.67 | <0.001 |
| POLE | 0.09 | 0.02-0.38 | <0.001 |