Table 3.
Multivariate Cox regression analyses for identifying clinicopathological parameters related to EC patients’ OS.
| Clinical feature | Multivariate analysis | ||
|---|---|---|---|
| HR | 95%CI of HR HR | P value | |
| Risk High | 4.40 | 2.32-8.35 | <0.001 |
| Age, y | 1.02 | 0.99-1.05 | 0.223 |
| AJCC stage | |||
| I | 1 (reference) | ||
| II | 1.29 | 0.37-4.44 | 0.687 |
| III | 4.11 | 2.11-8.00 | <0.001 |
| IV | 9.44 | 2.76-32.28 | <0.001 |
| Grade | |||
| Low | 1 (reference) | ||
| High | 2.73 | 1.22-6.11 | 0.014 |
| Margin_status | |||
| R0 | 1 (reference) | ||
| R1 | 1.05 | 0.36-3.10 | 0.929 |
| R2 | 0.82 | 0.28-2.37 | 0.714 |
| TCGA molecular classification | |||
| CN_HIGH | 1 (reference) | ||
| CN_LOW | 2.01 | 0.84-4.82 | 0.118 |
| MSI | 1.89 | 0.84-4.25 | 0.123 |
| POLE | 0.31 | 0.07-1.41 | 0.129 |