TABLE 1.
Weight, glucose, and blood parameters at the study endpoint.
| Control (n = 8) | EMPA (n = 8) | SNT (n = 12) | SNT + EMPA (n = 12) | |
|---|---|---|---|---|
| Body weight (g) | 24.33 ± 1.14 | 23.59 ± 1.17 | 23.22 ± 1.18 | 23.68 ± 1.17 |
| Heart weight (mg) | 116.25 ± 10.61 | 112.50 ± 10.35 | 115.83 ± 13.11 | 112.5 ± 9.65 |
| Lung weight (mg) | 136.25 ± 10.61 | 132.50 ± 8.86 | 135.83 ± 9.96 | 131.67 ± 10.30 |
| Heart weight/Body weight (mg/g) | 4.77 ± 0.27 | 4.76 ± 0.32 | 4.98 ± 0.44 | 4.75 ± 0.30 |
| Lung weight/Body weight (mg/g) | 5.60 ± 0.24 | 5.62 ± 0.25 | 5.86 ± 0.45 | 5.56 ± 0.21 |
| Heart weight/tibial length (mg/mm) | 6.22 ± 0.57 | 6.12 ± 0.52 | 6.37 ± 0.63 | 6.22 ± 0.44 |
| Blood glucose (mmol/L, fasting) | 5.64 ± 0.63 | 5.46 ± 0.66 | 5.52 ± 0.64 | 5.35 ± 0.66 |
| Plasma cTnT (pg/ml) | 276.28 ± 106.15 | 234.88 ± 164.93 | 1,468.87 ± 335.18* | 724.55 ± 209.28# |
| Plasma NT-proBNP (pg/ml) | 11.38 ± 1.12 | 11.58 ± 1.74 | 17.81 ± 5.52* | 11.06 ± 3.93# |
Data are expressed as the mean ± SD. cTnT: cardiac troponin T, NT-proBNP: N-terminal pro–B-type natriuretic peptide. p <0.05 vs. control, # p < 0.05 vs. SNT.