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. 2021 Feb 26;6(5):1232–1241. doi: 10.1016/j.ekir.2021.02.017

Table 5.

Net benefit of immediate transplant during a pandemic compared to deferred transplant outside of a pandemic: relatively higher infection rates and case fatality rates (CFR)

Age (yr) Baseline
[95% CI]
1.5-fold higher CFR in transplant recipients relative to dialysis/wait list 1.5 Higher infection rate in transplant relative to dialysis/wait list 1.5 Higher infection rate in wait list;
1.5-fold higher CFR in transplant
1.5 Higher infection rate in wait list; CFR 2-fold higher in transplant than wait list
25
LYs 0.48 [0.12–0.84] 0.26 [–0.13 to 0.60] 0.21 [–0.13 to 0.55] 0.42 [0.08–0.76] 0.20 [–0.13 to 053]
QALYs 0.63 [0.23–1.03] 0.42 [0.06–0.78] 0.35 [–0.03 to 0.73] 0.57 [0.17–0.97] 0.36 [–0.04 to 0.76]
40
LYs 1.32 [1.06–1.58] 1.10 [0.85–1.35] 1.04 [0.79–1.29] 1.25 [0.99–1.51] 1.03 [0.76–1.20]
QALYs 1.63 [1.35–1.91] 1.42 [1.12–1.72] 1.35 [1.05–1.65] 1.56 [1.27–1.85] 1.35 [1.06–1.64]
50
LYs 1.32 [1.17–1.47] 0.81 [0.66–0.96] 0.83 [0.68–0.98] 1.15 [0.98–1.32] 0.66 [0.51–0.81]
QALYs 1.67 [1.50–1.84] 1.18 [1.00–1.36] 1.18 [1.00–1.36] 1.50 [1.32–1.68] 1.02 [0.84–1.20]
60
LYs 0.90 [0.81–0.98] 0.15 [0.07–0.23] 0.23 [0.16–0.30] 0.65 [0.57–0.73] –0.06 [–0.16 to 0.04]
QALYs 1.23 [1.13–1.33] 0.28 [0.18–0.38] 0.56 [0.46–0.66] 0.96 [0.86–1.06] 0.27 [0.16–0.38]
70
LYs 0.32 [0.26–0.38] –0.33 [–0.39 to –0.27] –0.25 [–0.29 to –0.21] 0.13 [0.08–0.18] –0.47 [–0.53 to –0.41]
QALYs 0.62 [0.57–0.67] –0.01 [–0.07 to 0.05] 0.06 [0.01–0.11] 0.41 [0.32–0.50] –0.18 [–0.24 to –0.12]

Based on 12,000 cases per 100,000 patient years in general population; 24,000 cases per 100,000 (end-stage kidney disease) ESKD patient years; 1.5-fold higher in wait list patients is equal to 36,000 case per 100,000 per wait list patient years. LYs, life years; QALYs, quality adjusted life years.