Table 3.
Characteristics of donors with predonation and postdonation hypertension
| Predonation hypertension, n = 904 | Postdonation hypertension, n = 2319 | P value | |
|---|---|---|---|
| Donation to last follow-up, yr, mean ± SD | 14.3 ± 10.1 | 21.2 ± 11.1 | <0.001 |
| Age, yr, median (IQR) | 48 (38–55) | 40 (31–48) | <0.001 |
| <35, n (%) | 171 (18.9) | 774 (33.4) | |
| 35–50, n (%) | 358 (39.6) | 1094 (47.2) | |
| >50, n (%) | 375 (41.5) | 451 (19.4) | |
| Male, n (%) | 451 (49.9) | 1176 (50.7) | 0.67 |
| Race/ethnicity, n (%) | 0.10 | ||
| Non-Hispanic white | 766 (84.7) | 1990 (85.8) | |
| Non-Hispanic black | 99 (11.0) | 214 (9.2) | |
| Hispanic | 11 (1.2) | 30 (1.3) | |
| Asian | 8 (0.9) | 12 (0.5) | |
| Other | 5 (0.6) | 38 (1.6) | |
| Unknown | 15 (1.7) | 35 (1.5) | |
| Related to recipient, n (%) | 665 (73.9) | 2002 (86.5) | <0.001 |
| First-degree relative with hypertension, n (%) | 405 (48.4) | 838 (39.4) | <0.001 |
| First-degree relative with diabetes, n (%) | 324 (38.4) | 884 (40.5) | 0.28 |
| First-degree relative with kidney disease, n (%) | 554 (64.0) | 1747 (77.7) | <0.001 |
| First-degree relative with heart disease, n (%) | 335 (40.2) | 661 (31.2) | <0.001 |
| College or higher education level, n (%) | 459 (50.8) | 1000 (43.1) | <0.001 |
| Weight, kg, median (IQR) | 82.6 (72.1–94.8) | 77.9 (66.4–89.9) | <0.001 |
| BMI, kg/m2, median (IQR) | 28.0 (25.0–31.1) | 26.3 (23.4–29.6) | <0.001 |
| Fasting glucose, mg/dl, median (IQR) | 96 (89–103) | 93 (86–101) | <0.001 |
| SBP, mm Hg, median (IQR) | 143 (140–148) | 124 (117–130) | <0.001 |
| DBP, mm Hg, median (IQR) | 83 (77–88) | 76 (71–81) | <0.001 |
| One artery in nondonated kidney, n (%) | 658 (73) | 1636 (71) | 0.19 |
| Left kidney removed, n (%) | 591 (67) | 1463 (65) | 0.24 |
| Creatinine, mg/dl, median (IQR) | 1.0 (0.8–1.1) | 1.0 (0.8–1.1) | 0.31 |
| eGFR, ml/min/1.73 m2, median (IQR) | 83 (71–96) | 87 (76–101) | <0.001 |
BMI, body mass index; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; IQR, interquartile range; SBP, systolic blood pressure; SD, standard deviation.