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. 2021 Apr 29;8:646408. doi: 10.3389/fvets.2021.646408

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Copyright © 2021 Xiao, Zhou, Sun, Wang, Wu and Bao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of DNA methylation on the MUC2 gene promoter activity. pGL3-basic: empty plasmid; Methylated: pGL3-MUC2 recombinant plasmid were treated with M.SssI; Control: pGL3-MUC2 recombinant plasmid was not methylated. Both Methylated group and Control group contained the promoter sequence analyzed in this study. **P < 0.01.