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. 2021 May 12;4(5):e2110452. doi: 10.1001/jamanetworkopen.2021.10452

Table. Drug Overdose Death Characteristics in San Francisco, California, in 8.5 Months Before and After COVID-19 Shelter-in-Place Health Order.

Characteristic Unintentional overdose deaths, No. (%) P valuea
July 1, 2019, to March 16 2020 March 17 to Novenver 30, 2020
Total overdose deaths, No. 365 537 <.001
Median overdose deaths per week (IQR) 10 (7-12) 15 (11-18) <.001
Demographic characteristics
Age group, y
<15 0 0 .85
15-24 12 (3) 19 (4)
25-44 139 (38) 208 (39)
45-64 171 (47) 257 (48)
≥65 40 (11) 51 (10)
Unknown 3 (<1) 2 (<1)
Sex
Men 286 (78) 442 (82) .14
Women 79 (22) 95 (18)
Race/ethnicity
Asian 10 (3) 22 (4) .02
Black 106 (29) 131 (24)
White/Latinxb 212 (58) 353 (66)
Other 4 (1) 7 (1)
Unknown 33 (9) 24 (4)
Decedents experiencing homelessness 85 (23) 183 (34) .001
Substance implicated as cause of deathc
Fentanyl 226 (62) 388 (72) .001
Heroin 76 (21) 67 (12) .001
Other opioids 40 (11) 52 (10) .53
Methamphetamine 193 (53) 309 (58) .17
Cocaine 184 (50) 185 (34) <.001
Location of death
Hospital 41 (11) 79 (15) .13
Hotel or motel 20 (5) 27 (5) .77
Outdoors 80 (22) 136 (25) .24
Shelter 3 (1) 4 (1) .90
Shelter-in-place sitesd NA 21 (4) NA
Private indoors, eg, residences, commercial buildings 221 (61) 270 (50) .002

Abbreviations: IQR, interquartile range; NA, not applicable.

a

Proportions were compared using χ2 tests; medians were compared using Wilcoxon rank sum tests.

b

Race/ethnicity data during this time period were not disaggregated to allow for distinction between White and Latinx deaths.

c

Not mutually exclusive.

d

Shelter-in-place sites were established by the city in April 2020 to place individuals from existing congregate shelters, hospitals, or the street. Individuals susceptible to COVID-19 (ie, those aged >60 years and/or with health conditions) were prioritized.