Table 2.
Effects of S. yapa leaves extract on survival parameters of bearing mice.
| Parameters | Groups |
||
|---|---|---|---|
| Tumor bearing | FU-treated (20 mg/kg/ day) | Extract treated (480 mg/kg/day) | |
| Tumor volume (cm3) | 3.00 ± 0.28 | 1.52 ± 0.16* | 0.855 ± 0.028* |
| % change | −49.33% | −71.50% | |
| Tumor weight | 3.59 ± 0.66 | 0.73 ± 0.15* | 0.522 ± 0.066* |
| % change | −79.67% | −85.46% | |
| MST (day) | 20 ± 0.18 | 41 ± 0.84* | 53.2 ± 0.142* |
| Increase in lifespan % | – | 105 ± 0.45 | 116 ± 0.817 |
Data are presented as mean of 5 animals ± SD followed with increasing or decreasing percentage as compared to tumor bearing mice. MST: median survival time. One-way ANOVA was used for data analysis followed by post Hoc test for multiple comparisons (n = 5, p < 0.05). Treated groups were compared to bearing group (*).