Table 5.

Efficacy of S. yapa extract on the liver function of tumor bearing mice in Ehrlich model.

Groups	ALT	AST	AST/ALT ratio
	U/L
Normal groups
Negative control	29.33 ± 1.02	25.83 ± 1.11	0.88 ± 0.21
Extract control group	29 ± 1.71	26.31 ± 1.31	0.91 ± 0.13
Ehrlich Ascites carcinoma bearing mice
Tumor bearing mice	110 ± 0.05**	450 ± 2.14**	4.09 ± 1.32**
FU treated group	90 ± 1.51*	192 ± 1.05*	1.92 ± 0.31*
% change	−18.18%	−57.33%	−53.06%
Extract treated group	77.9 ± 0.199*	180.5 ± 0.437*	2.194 ± 0.95*
% change	−29.18%	−59.88%	−46.45%

Data are presented as mean of five animals ± SD. One-way ANOVA was used for data analysis followed by post Hoc for multiple comparisons (n = 5, p < 0.05). Bearing mice and + ve controls were compared to –ve control group (**) while treated groups were compared to bearing group (*). FU; flouro uracil treated group, ALT; Glutamic- pyruvic transaminase, AST; Glutamic- oxaloacetic transaminase.