A, Kaplan-Meier survival analysis from baseline evaluation for the primary end point stratified according to the presence of left ventricular ejection fraction (LVEF) within reference ranges (LVEF ≥50%), mild to moderate left ventricular systolic dysfunction (LVSD) (LVEF 36%-49%), or severe LVSD (LVEF ≤35%) on transthoracic echocardiogram (TTE) or cardiac magnetic resonance (CMR) imaging for patients with FLNC truncating variants (FLNCtvs). B, Kaplan-Meier survival analysis from baseline evaluation for the arrhythmic secondary end point stratified according to the presence of LVEF within reference ranges, mild to moderate LVSD, or severe LVSD on TTE or CMR imaging for patients with FLNCtv. C, Kaplan-Meier survival analysis from baseline evaluation for the arrhythmic secondary end point stratified according to genetic variant (for TTN or FLNC) and the presence of baseline mild to moderate LVSD or severe LVSD on TTE or CMR imaging.