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. 2021 May 12;6(7):821–829. doi: 10.1001/jamacardio.2021.0961

Table 3. Multivariable Regression Coefficients for Systolic Blood Pressure in Multiple Regression Models of Key Left Ventricular Parameters Within Gestational Age Group Categoriesa.

CMR parameters Model Very and extremely preterm-born adults (<32 wk gestation) Moderately preterm-born adults (32-36 wk gestation) Term-born adults (≥37 wk gestation)
B (per 1–mm Hg SBP) 95% CI P value B (per 1–mm Hg SBP) 95% CI P value B (per 1–mm Hg SBP) 95% CI P value
Lower bound Upper bound Lower bound Upper bound Lower bound Upper bound
Myocardium Mass/BSA, g/m2 Unadjusted 0.475 0.297 0.654 <.001 0.281 0.135 0.427 <.001 0.288 0.189 0.387 <.001
Adjusted 0.394 0.213 0.574 <.001 0.250 0.113 0.387 <.001 0.157 0.060 0.254 .002
Ejection fraction, % Unadjusted 0.068 −0.036 0.171 .20 −0.010 −0.102 0.082 .84 0.066 0.010 0.123 .02
Adjusted 0.100 −0.015 0.216 .09 −0.031 −0.129 0.067 .53 0.079 0.017 0.140 .01
ED volume/BSA, mL/m2 Unadjusted 0.170 0.010 0.330 .04 0.192 −0.001 0.386 .05 0.139 0.005 0.273 .04
Adjusted 0.157 −0.016 0.329 .07 0.179 −0.011 0.393 .07 0.092 −0.043 0.228 .18
Mass/ED volume, g/mL Unadjusted 4.47 × 10−3 2.16 × 10−3 6.78 × 10−3 <.001 1.53 × 10−3 −5.40 × 10−5 3.12 × 10−3 .06 2.44 × 10−3 1.22 × 10−3 3.67 × 10−3 <.001
Adjusted 3.56 × 10−3 1.01 × 10−3 6.11 × 10−3 .007 1.04 × 10−3 −6.83 × 10−4 2.74 × 10−3 .24 1.08 × 10−3 −2.31 × 10−4 2.40 × 10−3 .11

Abbreviations: B, unstandardized coefficients with 95% confidence intervals; BSA, body surface area; CMR, cardiac magnetic resonance; ED, end-diastole; SBP, systolic blood pressure.

a

The regression coefficients for systolic blood pressure with the individual CMR parameters (dependent variables) are shown for both unadjusted (bivariate) and adjusted (multivariable) regression models. In multivariable models, independent variables were systolic blood pressure, age, sex, birth weight z score, and body mass index (multivariable regression coefficients shown for systolic blood pressure).