Table. Main Characteristics of Patients With Delayed Localized Cutaneous Hypersensitivity Reactions to the Moderna Coronavirus Disease 2019 Vaccine.

Patient No.	Prior allergies	First-dose reaction				Second-dose reaction
		Onset, d	Duration, d	Other symptoms	Treatment	Onset, d	Duration, d	Other symptoms	Treatment
1	Amoxicillin/clavulanic acid, TMP-SMX	9	15	None	None	No reaction	NA	Nausea, chills, myalgias, headache, sore arm	NA
2	None	2	14	Fevers, chills, arthralgias, myalgias, headache, fatigue	None	No reaction	NA	Fatigue, myalgias, headaches	NA
3	None	8	5	Sore arm	Clobetasol ointment	1	3	Headache, myalgias, chills, sore arm	Clobetasol ointment
4	Seasonal allergies	12	1	None	None	3	2	Myalgias, chills	None
5	Seasonal allergies	7	6	None	None	0	2	Headache, fatigue, sore arm	Antihistamine
6	None	7	2	None	Antihistamine	5	1	Headache, chills, joint pain	None
7	None	7	3	None	Clobetasol ointment	1	2	Malaise, fevers, fatigue, headache	Clobetasol ointment
8	Cephalexin	8	7	Sore arm	Clobetasol ointment and antihistamine	1	3	Fatigue, decreased appetite, sore arm	Clobetasol ointment and antihistamine
9	Amoxicillin/clavulanic acid, TMP-SMX	3	4	Sore arm	None	1	4	Headache, fatigue, chills	None
10	Seasonal and food allergies	7	5	None	Cephalexin	No reaction	NA	Fever, headache, fatigue	NA
11	None	7	4	Fatigue	None	2	2	Fever, headache, neck pain, arthralgias	None
12	TMP-SMX	7	21	Sore arm	Antihistamine	2	5	Lethargy	None
13	None	6	7	None	Cool compresses	2	5	None	None
14	Seasonal and food allergies	No reaction	NA	Sore arm	NA	2	4	Fevers, chills, myalgias, rigors	None
15	None	2	5	Fatigue	Hydrocortisone cream	2	5	Fever, headache, fatigue	Hydrocortisone cream
16	None	9	2	Sore arm	None	No reaction	NA	Sore arm	NA

Abbreviations: NA, not applicable; TMP-SMX, trimethoprim-sulfamethoxazole.