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. Author manuscript; available in PMC: 2022 Jun 25.
Published in final edited form as: Behav Brain Res. 2021 Mar 29;408:113267. doi: 10.1016/j.bbr.2021.113267

Fig. 3. DAT-Ala53 mice exhibit hyperlocomotion to novel environment.

Fig. 3.

Naive male WT (n = 24) and DAT-Ala53 (n = 24) animals were placed in the locomotor boxes on day 1 without prior habituation and then on subsequent days 2 and 3, and motor activity were monitored for 60 min. Representative activity traces show the locomotor activity of WT and DAT-Ala53 mice on day 1 (A) and day 3 (B). Time course plots show distance traveled, vertical counts, and stereotypy counts measured in 4 min bins over 60 min period on day one (C, D, E) and on day three (F, G, H). Comparative analysis (DAT-Ala53 vs. WT) of total distance traveled (I), vertical counts (J) and stereotypy counts (K) are shown. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001 (Day 1), ns: nonsignificant effect (P > 0.9999) compared to WT (Day 3). ΛΛΛΛ P <0.0001, compared between specified pairs. Data are presented as Means ± S.D. Two-way ANOVA followed by Bonferroni’s multiple comparison test