Table I.
Parameter | Normal geometry (n = 718) | Concentric hypertrophy (n = 314) | Eccentric hypertrophy (n = 121) | P-value |
---|---|---|---|---|
Demographic data: | ||||
Age | 65.7 ±20 | 66.9 ±16.5 | 68.7 ±18.7 | 0.01 |
Male gender | 464 (67) | 172 (55) | 58 (48) | < 0.001 |
Race: | ||||
White | 421 (59) | 159 (51) | 70 (58) | 0.054 |
Black | 236 (33) | 138 (44) | 43 (36) | 0.002 |
BMI | 28.4 ±7.2 | 28.8 ±7.1 | 27.6 ±7.4 | 0.146 |
Hypertension | 583 (81) | 292 (93) | 110 (91) | < 0.001 |
Dyslipidemia | 538 (75) | 246 (78) | 97 (80) | 0.29 |
Diabetes | 317 (44) | 171 (54) | 66 (55) | 0.003 |
Smoker | 168 (23) | 87 (28) | 26 (21) | 0.24 |
FamHx of CAD | 138 (19) | 51 (16) | 19 (16) | 0.40 |
Current dialysis | 23 (3.2) | 44 (14) | 13 (11) | < 0.001 |
Chronic lung disease | 43 (6) | 24 (8) | 10 (8) | 0.47 |
Prior MI | 137 (19) | 88 (28) | 35 (29) | 0.001 |
Prior HF | 62 (9) | 87 (28) | 43 (36) | < 0.001 |
Prior CVD | 68 (9) | 42 (13) | 17 (14) | 0.09 |
Prior PAD | 55 (8) | 22 (7) | 17 (14) | 0.04 |
Prior valve Sx | 5 (0.6) | 8 (3) | 1 (0.8) | 0.04 |
Prior PCI | 197 (27) | 143 (46) | 63 (52) | < 0.001 |
Prior CABG | 48 (7) | 30 (10) | 20 (17) | 0.001 |
Prior cardiogenic shock | 17 (2) | 2 (0.6) | 1 (0.8) | 0.10 |
Prior cardiac arrest | 16 (2) | 5 (2) | 2 (2) | 0.76 |
STEMI | 383 (53) | 116 (37) | 54 (45) | < 0.001 |
Echocardiographic and laboratory data: | ||||
IVS [cm] | 1.05 ±0.3 | 1.4 ±0.3 | 1.09 ±0.2 | < 0.001 |
LVIDd [cm] | 4.4 ±0.8 | 4.8 ±0.9 | 5.7 ±0.7 | < 0.001 |
PWD [cm] | 1.03 ±0.2 | 1.34 ±0.2 | 1.0 ±0.2 | < 0.001 |
RWT | 0.47 ±0.15 | 0.57 ±0.1 | 0.4 ±0.1 | < 0.001 |
LVMI | 82.7 ±24 | 137.7 ±36 | 130.1 ±31 | < 0.001 |
LVEF | 51.9 ±18 | 47.8 ±25 | 39.2 ±30 | < 0.001 |
Peak troponin I [ng/ml] | 5.8 ±29.8 | 3.0 ±26.0 | 4.8 ±24.3 | 0.06 |
CABG – coronary artery bypass graft, CVD – cerebral vascular disease, FamHx of CAD – family history of coronary artery disease, HF – heart failure, IVS – intraventricular septal diameter, MI – myocardial infarction, LVIDd – left ventricular inner diameter at end diastole, LVEF – left ventricular ejection fraction, LVMI – left ventricular mass index, PAD – peripheral artery disease, PCI – percutaneous coronary intervention, PWD – posterior wall diameter, RWT – relative wall thickness, STEMI – ST-segment elevation myocardial infarction, sx – surgery.