TABLE 2.
Representative circRNA-mediated ceRNETs in glioma.
| circRNA | Competitor (mRNA) | Shared miRNA(s) | ceRNA role | Related glioma hallmark | References |
| circPOSTN | TPX2 | miR-361-5p | Oncogenic | Proliferation, cell growth, and apoptosis | Long et al., 2020 |
| ? | miR-1205 | Cell growth, migration, invasion, and apoptosis | Yang Y. et al., 2019 | ||
| circCPA4 | CPA4 | miR-let-7 | Oncogenic | Proliferation and invasion | Peng et al., 2019 |
| MEF2D | miR-760 | Proliferation, migration, invasion, apoptosis, and radiosensitivity | Zhang Y. et al., 2020 | ||
| circ_0001946 | CDR1 | miR-671-5p | Tumor suppressive | Proliferation, migration, invasion, and apoptosis | Li and Diao, 2019 |
| circMMP9 | CDK4 and AURKA | miR-124 | Oncogenic | Proliferation, migration, and invasion | Wang et al., 2018 |
| circASAP1 | NRAS | miR-502-5p | Oncogenic | Proliferation, apoptosis, and chemoresistance | Wei et al., 2020 |
| circPITX1 | IL17RD | miR-518a-5p | Oncogenic | Proliferation, migration, invasion, and apoptosis | Zhan et al., 2019 |
| ERBB4 | miR-1304 | Proliferation, migration, invasion, and apoptosis | Chen M. et al., 2020 | ||
| MAP3K2 | miR-379-5p | Proliferation and apoptosis | Lv et al., 2019 | ||
| NEK2 | miR-329-3p | Cell growth, colony formation, and radiosensitivity | Guan et al., 2020 | ||
| circPCMTD1 | mTOR | miR-224-5p | Oncogenic | Cell viability, proliferation, migration, and invasion | Zheng et al., 2019 |
| circSCAF11 | SP1 | miR-421 | Oncogenic | Proliferation and invasion | Meng et al., 2019 |
| circEZH2 | DDAH1 and CBX3 | miR-1265 | Oncogenic | Cell growth, migration, invasion, and apoptosis | Gao et al., 2020 |
| hsa_circ_0000177 | FZD7 | miR-638 | Oncogenic | Proliferation and invasion | Chen and Duan, 2018 |
| circITCH | ITCH | miR-214 | Tumor suppressive | Proliferation, migration, and invasion | Li F. et al., 2018 |
| circNFIX | NOTCH1 | miR-34a-5p | Oncogenic | Proliferation, migration, and apoptosis | Xu H. et al., 2018 |
| hsa_circ_0007534 | ZIC5 | miR-761 | Oncogenic | Proliferation and migration | Li G.F. et al., 2018 |
| hsa_circ_0046701 | ITGB8 | miR-142-3p | Oncogenic | Proliferation and invasion | Li G. et al., 2018 |
| circTTBK2 | miR-761 | Oncogenic | Proliferation, invasion, and ferroptosis | Zhang H.Y. et al., 2020 | |
| circCFH | AKT1 | miR-149 | Oncogenic | Proliferation and colony formation | Bian et al., 2018 |
| circHIPK3 | IGF2BP3 | miR-654 | Oncogenic | Proliferation and invasion | Jin et al., 2018 |
| CCND2 | miR-124 | Proliferation, migration, and invasion | Liu Z. et al., 2020 | ||
| WEE1 | miR-124-3p | Proliferation, invasion, and EMT | Xia et al., 2020 | ||
| KIF2A | microRNA-524-5p | Proliferation, invasion, apoptosis, and chemoresistance | Yin and Cui, 2020 | ||
| circTTBK2 | HNF1β | miR-217 | Oncogenic | Proliferation, migration, invasion, and apoptosis | Zheng et al., 2017 |
| circSHKBP1 | FOXP1 | miR-544a | Oncogenic | Proliferation, migration, and angiogenesis | He et al., 2018 |
| FOXP2 | miR-379 | ||||
| hsa_circ_0088732 | RAB3D | miR-661 | Oncogenic | Migration, invasion, EMT, and apoptosis | Jin et al., 2020 |
| circPTN | SOX6 | miR-122 | Oncogenic | Proliferation and apoptosis | Chen C. et al., 2020 |
| circHECTD1 | SLC10A7 | miR-296-3p | Oncogenic | Proliferation and invasion | Li et al., 2021 |
| circSFMBT2 | MTSS1 | miR-182-5p | Tumor suppressive | Proliferation, migration, and invasion | Zhang S. et al., 2020 |
| circFANCL | HMGB1 | miR-337-3p | Oncogenic | Proliferation and apoptosis | Tao et al., 2020 |
| has_circ_0012129 | TGIF2 | miR-761 | Oncogenic | Cell viability, proliferation, colony formation, migration, invasion, and apoptosis | Xu et al., 2020 |
| circ_0079593 | KPNA2 | miR-499a-5p | Oncogenic | Proliferation, migration, and apoptosis | Yang et al., 2020 |
| circ_0000215 | CXCR2 | miR-495-3p | Oncogenic | Proliferation, invasion, EMT, and apoptosis | Mutalifu et al., 2020 |
| circABCB10 | FABP5 | miR-620 | Oncogenic | Proliferation, migration, invasion, and apoptosis | Sun W.Y. et al., 2020 |
| hsa_circ_0076248 | SIRT1 | miR-181a | Oncogenic | Proliferation, invasion, and chemoresistance | Lei and Huang, 2019 |
| circ_0034642 | BATF3 | miR-1205 | Oncogenic | Proliferation, migratory, invasion, and apoptosis | Yang M. et al., 2019 |
| circU2AF1 | NOVA2 | miR-7-5p | Oncogenic | Proliferation migration, invasion, and apoptosis | Li G. et al., 2019 |
| circ_002136 | SOX13 | miR-138-5p | Oncogenic | Migration, invasion, and angiogenesis | He Z. et al., 2019 |
| circDICER1 | ZIC4 | miR-103a-3p and miR-382-5p | Oncogenic | Proliferation, migration, and angiogenesis | He Q. et al., 2019 |
| hsa_circ_0074362 | HOXB7 | miR-1236-3p | Oncogenic | Proliferation, migration, and invasion | Duan et al., 2018 |
| circELF2 | MUC15 | miR-510-5p | Oncogenic | Cell growth, migration, invasion, and apoptosis | Zhang and Xu, 2020 |
| hsa_circ_0000337 | MAT2A | miRNA-942-5p | Oncogenic | Proliferation, migration, and invasion | Liu N.Z. et al., 2020 |
| circ_0079586 | MDM4 | miR-183-5p | Oncogenic | Cell growth, migration, invasion, and apoptosis | Chen J. et al., 2020 |
| circENTPD7 | ROS1 | miR-101-3p | Oncogenic | Proliferation, migration, and invasion | Zhu et al., 2020a |
| circEPHB4 | SOX10 | miR-637 | Oncogenic | Stemness, proliferation, and glycolysis | Jin et al., 2021 |
| circTOP2A | SUSD2 | miR-346 | Oncogenic | Cell viability, migration, invasion, and apoptosis | Sang et al., 2021 |
| circ_101064 | PIWIL1 | miR-154-5p | Oncogenic | Proliferation, invasion, and migration | Zhou H. et al., 2020 |
| circ_0000020 | PIK3CA | miR-142-5p | Oncogenic | Proliferation, migration, and invasion | Wang and Zhu, 2021 |
?Undefined.