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. 2021 Apr 29;12:670681. doi: 10.3389/fmicb.2021.670681

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Copyright © 2021 Silva, Matias, Romão and Saraiva.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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E. coli YtfE Iron center. (A) YtfE^M di-iron center is coordinated by residues H84, H129, E133, H160, H204, and E208. (B) YtfE^M-E159L mononuclear Fe center is coordinated by H84, H204 and E208. The second Fe atom is not present and residue H129 assumes a different side chain conformation from that in YtfE^M. (C) In YtfE^M-E125L the di-iron center, is structurally similar to in YtfE^M.