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. 2021 May 12;12:284. doi: 10.1186/s13287-021-02359-w

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 8 — Pathological characteristics of xenografts. HE staining showed that the cells in the mass were arranged close together and that the cytoplasmic ratio was relatively large (a), which conformed to the morphology of tumor tissue. Prussian blue staining (b) and TEM (c) showed a large amount of iron particles in the mass tissue in the MTMSC-PEG3-FTH1 and MTMSC-CMV-FTH1 groups but not in the MTMSC group. The intratumoral iron content (d) was not significantly different between the MTMSC-PEG3-FTH1 and MTMSC-CMV-FTH1 groups but was significantly higher in both of these groups than in the MTMSC group (***P<0.001)