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. 2021 Apr 29;12:675678. doi: 10.3389/fimmu.2021.675678

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Copyright © 2021 Della-Torre, Lanzillotta, Campochiaro, Cavalli, De Luca, Tomelleri, Boffini, De Lorenzo, Ruggeri, Rovere-Querini, Castagna, Landoni, Tresoldi, Ciceri, Zangrillo and Dagna

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cumulative incidence of long-term survival of patients treated with biologic drugs compared to patients treated with standard of care: entire patient cohort. Kaplan-Meier curves showing the cumulative incidence of overall survival up to 186 days of the entire cohort of patients treated with biologic drugs (A), anakinra (B), sarilumab (C), and tocilizumab (D) compared to patients treated with standard of care. Time to death is expressed in days from the day of enrolment. A, anakinra; B, biologic drugs; C, comparators treated with standard of care; S, sarilumab; T, tocilizumab; HR, hazard ratio; CI, confidence interval. Statistically significant p value < 0.05.