Table 1.
Clinical and serological features of the patient cohort.
| Biologics(n=107) | Standard of care(n=103) | p value | |
|---|---|---|---|
| Age (years) | 61 (54-72) | 62 (57-72) | 0.15 |
| Male sex, n (%) | 67 (62.6%) | 57 (55%) | 0.33 |
| Comorbidities | |||
| HBP | 39 (35%) | 44 (43%) | 0.49 |
| CAD | 11 (10%) | 18 (17%) | 0.17 |
| Type 2 diabetes | 17 (16%) | 21 (20%) | 0.38 |
| COPD | 4 (4%) | 7 (7%) | 0.36 |
| Cancer | 5 (5%) | 8 (8%) | 0.58 |
| CRF | 7 (7%) | 7 (7%) | 0.99 |
| PaO2/FiO2 ratio (mmHg) | 91 (75-132) | 105 (79-188) | 0.1 |
| Laboratory values | |||
| LAD (125-220 IU/L) | 453 (377-579) | 474 (383-606) | 0.38 |
| CRP (< 6 mg/L) | 154 (111-219) | 167.6 (124.8-231) | 0.11 |
| Ferritin (30-400 ng/mL) | 1542 (1009-3030) | 2260 (1237-3450) | 0.11 |
| IL6 (<7 pg/mL) | 57 (37-117) | 68.9 (34.65-162) | 0.63 |
Results are reported as median (interquartile range) unless specified; statistically significant p value < 0.05. HBP, high blood pressure; CAD, coronary artery disease; COPD, chronic obstructive pulmonary disease; CRF, chronic renal failure; LAD, lactate dehydrogenase; CRP, C-reactive protein; IL-6, interleukin-6.