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. 2021 Apr 29;12:675678. doi: 10.3389/fimmu.2021.675678

Table 6.

Baseline univariate and multivariate predictors of mortality in patients treated with biologic drugs.

Univariate analysis Multivariate analysis
HR (95% CI) p value HR (95% CI) p value
Age 1.04 (0.99-1.08) 0.07 1.043 (1-1.09) 0.048
Sex (F) 1.039 (0.306-3.527) 0.95
HBP 1.28 (0.54-3.04) 0.574 .
CAD 4.89 (1.89-12.64) 0.001 1.95 (0.61-6.3) 0.27
PaO2/FiO2 ratio (mmHg) 0.98 (0.96-99) 0.01 0.98 (0.965-0.997) 0.045
LAD 1.004 (1.00-1.01) 0.002 1.004 (1.001-1.007) 0.01
CRP 1.001 (0.996-1.007) 0.61
Ferritin 1 (1-1) 0.65
IL-6 1 (0.99-1.01) 0.12

Results are reported as hazard ratio and 95% confidence interval; statistically significant p value < 0.05. HBP, high blood pressure; CAD, coronary artery disease; LAD, lactate dehydrogenase; CRP, C-reactive protein; IL-6, interleukin-6; HR, hazard ratio; CI, confidence interval.

Bold values indicate that the p values are statistically significant.