Skip to main content
. 2021 Apr 29;12:670695. doi: 10.3389/fgene.2021.670695

Table 2.

Similarities of hydra xeroderma pigmentosum (XP) proteins with those from other basal metazoans.

XP protein Name of the organism Number of amino acids Percent identity with Hydra Protein Percent similarity with Hydra Protein
XPA
Binds to damaged DNA and verifies the lesion
Trichoplax adhaerens (Placozoan) 266 44.3 77.0
Amphimedon queenslandica (Sponge) 281 38.2 72.1
Stylophora pistillata (Coral) 267 51.7 81.3
Pocillopora damicornis (Coral) 272 44.0 71.0
Nematostella vectensis (Sea anemone) 266 53.0 79.3
Acropora millepora (Coral) 247 48.2 82.0
XPB
Core component of TFIIH, 3'→5' ATP-dependent helicase
Trichoplax sp. H2 799 68.0 88.8
Amphimedon queenslandica 664 64.7 85.9
Stylophora pistillata 777 69.9 87.2
Pocillopora damicornis 792 71.2 88.9
Nematostella vectensis 796 70.5 88.4
Acropora millepora 794 71.0 89.7
XPD
Bridges the core and the CAK complexes of TFIIH, 5'→3' ATP-dependent helicase.
Trichoplax sp. H2 761 69.4 91.1
Amphimedon queenslandica 754 63.6 88.5
Stylophora pistillata 759 76.6 91.9
Pocillopora damicornis 759 76.9 92.6
Nematostella vectensis 735 75.7 92.8
Acropora millepora 759 77.7 91.8
Exaiptasia diaphana (Sea anemone) 782 74.1 88.6
XPF
DNA endonuclease which incises damaged strand at 5' junction of the NER bubble.
Trichoplax sp. H2 846 45.1 75.6
Amphimedon queenslandica 917 40.7 70.9
Stylophora pistillata 917 46.8 73.0
Exaiptasia diaphana 849 43.4 69.6
Nematostella vectensis 915 47.5 73.8
Acropora millepora 918 48.3 73.0