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. 2021 Mar 24;80(10):1306–1311. doi: 10.1136/annrheumdis-2021-220272

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

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SARS-CoV-2 specific antibodies are detectable in patients and healthy controls. (A) Anti-SARS-CoV-2 IgG antibodies in patients with CID and controls 7 days after secondary immunisation. (B) IgG titres in patients with CID and controls at baseline on the day of the second immunisations and 7 days later. (C) Neutralising activity at 7 days post secondary immunisation. (D) Change in neutralising antibodies from baseline to day 7 after the second immunisation. (E) Anti-SARS-CoV-2 IgA levels 1 week after the second mRNA vaccination in patients and controls. (E) IgA titres at baseline and 7 days after second vaccination. Anti-SARS-CoV2-IgG titres (G) and neutralising capacity (H) in healthy controls and patients by age group 7 days after secondary vaccination. Each symbol represents a single study participant. Bars represent means. Cut-offs for commercial test are displayed as horizontal dashed lines. CID, chronic inflammatory disease; HCo, healthy control.