Table 1.
Comparison of DT/KT Metrics (Upper Panel) and 18F-FET PET Parameters (Bottom Panel) in the TRC and TPR Groups
| Parameter | TRC (n = 11) | TPR (n = 21) | P | |
|---|---|---|---|---|
| MD | Mean | 1.54 (1.42/1.7) | 1.32 (1.24/1.55) | .060 |
| C5 | 1.00 (0.94/1.10) | 0.93 (0.80/1.02) | .065 | |
| C10 | 1.13 (1.05/1.18) | 1.02 (0.87/1.1) | .023* | |
| RD | Mean | 1.54 (1.31/1.63) | 1.21 (1.13–1.43) | .034* |
| C5 | 0.92 (0.85/1.00) | 0.80 (0.66/0.86) | .020* | |
| C10 | 0.99 (0.96/1.10) | 0.87 (0.73/0.94) | .008* | |
| AD | Mean | 1.84 (1.69/1.91) | 1.57 (1.46/1.83) | .100 |
| C5 | 1.24 (1.13/1.30) | 1.14 (0.96/1.30) | .197 | |
| C10 | 1.32 (1.20/1.37) | 1.20 (1.03/1.35) | .171 | |
| MK | Mean | 0.50 (0.48/0.58) | 0.61 (0.57/0.69) | .002** |
| C90 | 0.61 (0.55/0.73) | 0.78 (0.70/0.83) | .001** | |
| C95 | 0.68 (0.57/0.77) | 0.82 (0.76/0.90) | .001** | |
| RK | Mean | 0.52 (0.50/0.60) | 0.63 (0.58/0.68) | .002** |
| C90 | 0.65 (0.57/0.76) | 0.81 (0.73/0.88) | .002** | |
| C95 | 0.74 (0.59/0.80) | 0.88 (0.78/0.98) | .002** | |
| AK | Mean | 0.51 (0.48/0.55) | 0.59 (0.55/0.65) | .002** |
| C90 | 0.62 (0.56/0.68) | 0.73 (0.67/0.79) | .003* | |
| C95 | 0.68 (0.61/0.76) | 0.78 (0.72/0.86) | .015* | |
| [18F]-FET PET | TBRmean | 2.00 (1.83/2.08) | 2.00 (1.90/2.23) | .200 |
| TBRmax | 2.50 (2.13/3.20) | 3.30 (2.75/3.93) | .012** | |
| TTP | 37.50 (37.5/27.5) | 27.50 (32.5/22.5) | .067 | |
| Slope | 0.42 (0.65/0.32) | 0.25 (0.61/0.03) | .210 |
3D ROI histogram parameters (the means and the centiles) of the DT/KT metrics and FET PET parameters are presented by their medians and quartiles (Q1/Q3 in parentheses) and by P values of the intergroup comparisons. Diffusivities are given in units of μm2/ms. Significant (Bonferroni corrected) comparisons are indicated by **, suggestively significant (non-corrected) by *.