Table 3.
Descriptive characteristics of tertiles of LDL aggregation in subjects with peripheral artery disease undergoing lower extremity revascularization.
| LDL-aggregation Tertile 1 | LDL-aggregation Tertile 2 | LDL-aggregation Tertile 3 | p-value for trend | |
|---|---|---|---|---|
| n=80 | n=79 | n=80 | ||
| Age, mean (SD), years | 73.5(12.2) | 72.7 (9.8) | 70.3 (11.0) | 0.15 |
| Female sex, n (%) | 28 (35.0) | 28 (35.4) | 22 (27.5) | 0.31 |
| BMI, mean (SD), kg/m2 | 26.8 (5.6) | 27.2 (5.1) | 26.3 (5.4) | 0.58 |
| LDL-cholesterol, mean (SD), mg/dL | 71 (27) | 75 (24) | 68 (23) | 0.97 |
| ApoB, mean (SD), mg/dL | 109 (27) | 107 (24) | 107 (22) | 0.93 |
| LDL-particles, mean (SD), nmol/L | 1147 (379) | 1232 (358) | 1145 (323) | 0.56 |
| LDL-particle size, mean (SD), nm | 20.5 (0.6) | 20.5 (0.6) | 20.3 (0.6) | 0.10 |
| HDL-cholesterol, mean (SD), mg/dL | 41 (11) | 43 (12) | 41 (10) | 0.23 |
| Triglycerides, median [range], mg/dL | 83 [31, 290] | 97 [35, 236] | 118 [41, 349] | <0.01 |
| Hypertension, n (%) | 68 (85.0) | 69 (87.3) | 68 (85.0) | 0.85 |
| Hyperlipidemia, n (%) | 63 (78.8) | 55 (69.6) | 59 (73.8) | 0.42 |
| Diabetes, n (%) | 36 (45.0) | 36 (45.6) | 46 (57.5) | 0.08 |
| Insulin use, n (%) | 28 (35.0) | 26 (32.9) | 21 (26.3) | 0.25 |
| Coronary artery disease, n (%) | 48 (60.0) | 43 (54.4) | 42 (52.5) | 0.43 |
| Prior myocardial infarction, n (%) | 16 (20.0) | 20 (25.3) | 19 (23.8) | 0.57 |
| Current smokers, n (%) | 9 (11.3) | 12 (15.2) | 17 (21.3) | 0.09 |
| Statin use, n (%) | 65 (81.5) | 62 (78.5) | 66 (82.5) | 0.65 |
| Aspirin use, n (%) | 63 (78.8) | 66 (83.5) | 69 (86.3) | 0.15 |
| Clopidogrel use, n (%) | 30 (37.5) | 26 (32.9) | 34 (42.5) | 0.58 |
SI conversion factors: To convert cholesterol to mmol/L, multiply values by 0.0259.
ASCVD – atherosclerotic cardiovascular disease
BMI – body mass index
LDL – low density lipoprotein
HDL – high density lipoprotein
PAD – peripheral artery disease
SD – standard deviation