Table 3.
Comparison of quantitative parameters of necrosis in three phases and iodine concentrations of the solid portion in arterial phase and venous phase with dual-energy spectral computed tomography between groups
| Quantitative parameters | NLC (n = 40) | NPMIL (n = 31) | p value |
|---|---|---|---|
| Necrosis | |||
| NCS | |||
| CT value at 70 keV (HU) | 19.16 ± 9.63 | 15.14 ± 7.66 | 0.061a |
| K40–65 keV | 0.31 ± 0.43 | − 0.21 ± 0.32 | < 0.001a |
| Effective atomic number | 7.63 ± 0.14 | 7.45 ± 0.13 | < 0.001a |
| AP | |||
| CT value at 70 keV (HU) | 22.80 ± 9.00 | 19.28 ± 6.95 | 0.076a |
| K40–65 keV | 0.29 ± 0.40 | 0.15 ± 0.34 | 0.043b |
| Effective atomic number | 7.65 ± 0.09 | 7.63 ± 0.09 | 0.119b |
| VP | |||
| CT value at 70 keV (HU) | 22.29 ± 7.98 | 19.13 ± 8.54 | 0.113a |
| K40–65 keV | 0.34 ± 0.54 | 0.15 ± 0.38 | 0.021b |
| Effective atomic number | 7.69 ± 0.17 | 7.68 ± 0.13 | 0.423b |
| Solid portion | |||
| IC in AP (mg/mL) | 1.37 ± 0.63 | 1.41 ± 0.80 | 0.977 b |
| IC in VP (mg/mL) | 1.48 ± 0.31 | 1.85 ± 1.01 | < 0.001b |
NLC, necrotic lung cancer; NPMIL, necrotic pulmonary mass-like inflammatory lesion; CT, computed tomography; K40–65 keV, the slope of the spectral curve from 40 to 65 keV; NCS, non-contrast-enhanced scanning; AP, arterial phase; VP, venous phase; IC, iodine concentration
a Two-independent-samples Student’s t-test
b Mann–Whitney U test