Table 4.
Receiver operating characteristic analyses of clinical characteristics and dual-energy spectral computed tomography quantitative parameters in necrotic lung cancer and pulmonary mass-like inflammatory lesions
| Characteristics | AUC (95% CI) | Optimal cut-off value | Sensitivity | Specificity |
|---|---|---|---|---|
| Age (years) | 0.747 (0.626–0.868) | 59 | 0.750 | 0.742 |
| Elevation of C-reactive protein concentration | 0.691 (0.566–0.815) | – | 0.806 | 0.575 |
| Quantitative parameters of necrosis | ||||
| K40–65 keV in NCS | 0.841 (0.749–0.933) | − 0.12 | 0.900 | 0.742 |
| K40–65 keV in AP | 0.641 (0.510–0.771) | 0.22 | 0.650 | 0.645 |
| K40–65 keV in VP | 0.660 (0.531–0.790) | 0.11 | 0.875 | 0.452 |
| Effective atomic number in NCS | 0.828 (0.731–0.926) | 7.54 | 0.825 | 0.774 |
| Quantitative parameters of solid portion | ||||
| IC in VP (mg/mL) | 0.754 (0.638–0.870) | 1.85 | 0.516 | 0.925 |
AUC, area under the receiver operating characteristic curve; CI: confidence interval; K40–65 keV, the slope of the spectral curve from 40 to 65 keV; NCS, non-contrast-enhanced scanning; AP, arterial phase; VP, venous phase; IC, iodine concentration