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. 2021 May 14;27(18):2160–2176. doi: 10.3748/wjg.v27.i18.2160

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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Effects of partially hydrolyzed guar gum on hepatic inflammation and fibrosis in the non-alcoholic fatty liver disease model. A: Tumor necrosis factor-α; B: Monocyte chemotactic protein-1; C: Collagen 1a1; D: α smooth muscle actin mRNA expression in the liver. mRNA expression was evaluated using real-time polymerase chain reaction. Data represent the mean ± SD of seven mice. ^aP < 0.05 significant differences compared to the control group; ^bP < 0.05 significant differences between the 2 selected groups. NAFLD: Non-alcoholic fatty liver disease; PHGG: Partially hydrolyzed guar gum; TNF-α: Tumor necrosis factor-α; MCP-1: Monocyte chemotactic protein-1; αSMA: α smooth muscle actin.