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. 2021 Apr 27;87(10):e02547-20. doi: 10.1128/AEM.02547-20

TABLE 1.

Correlation coefficients between rotavirus concentrations in sewage and oysters and between the number of rotavirus-associated gastroenteritis cases and virus concentrations in oysters or sewage calculated by two methods

Methoda and vaccine strain Correlation Correlation coefficient at the following lag time (wk)b:
−7 −6 −5 −4 −3 −2 −1 0 1 2 3 4 5 6 7
Method a
 Wild-type Sewage-
oysters		 0.31 0.50 0.45 0.55 0.48 0.39 0.48 0.47 0.18 0.37 0.23 0.23 0.10 0.37 −0.03
Patients-
oysters		 0.01 −0.18 0.07 −0.39 −0.13 −0.26 −0.53 −0.30 −0.47 0.01 0.03 −0.18 −0.28 −0.39 −0.22
Patients-
sewage		 0.29 0.45 0.37 −0.09 0.06 −0.10 0.06 −0.29 −0.27 −0.39 −0.03 −0.21 −0.20 0.06 0.08
 RotaTeq Sewage-
oysters		 −0.01 −0.33 0.45 0.13 −0.13 −0.01 −0.35 −0.25 0.22 0.13 0.20 −0.12 −0.06 0.13 0.32
Patients-
oysters		 −0.36 −0.34 −0.19 −0.35 −0.15 −0.29 −0.28 −0.35 −0.49 −0.31 −0.47 −0.26 −0.49 −0.39 −0.26
Patients-
sewage		 0.04 0.34 −0.03 −0.23 −0.18 −0.42 0.08 −0.17 0.11 0.00 0.15 0.09 −0.01 0.35 0.33
Method b
 Wild-type Sewage-
oysters		 0.24 0.32 0.31 0.46 0.43 0.31 0.38 0.34 0.22 0.28 0.15 0.02 −0.18 −0.33 −0.20
Patients-
oysters		 0.18 0.16 0.16 −0.01 0.06 −0.03 −0.07 −0.02 −0.24 −0.10 −0.23 −0.29 −0.22 −0.38 −0.44
Patients-
sewage		 −0.05 0.09 0.04 0.01 0.13 −0.06 0.01 0.00 0.10 0.14 0.13 0.12 0.22 0.26 0.36
 RotaTeq Sewage-
oysters		 −0.21 −0.46 −0.27 −0.22 −0.30 −0.23 −0.33 −0.17 0.03 0.02 −0.04 −0.07 −0.17 −0.12 −0.23
Patients-
oysters		 −0.23 −0.31 −0.31 −0.31 −0.31 −0.45 −0.33 −0.34 −0.42 −0.29 −0.32 −0.24 −0.26 −0.23 −0.28
Patients-
sewage		 0.10 0.28 0.20 0.30 0.24 0.19 0.31 0.28 0.42 0.37 0.36 0.33 0.43 0.49 0.55
a

Method a used only paired positive samples of oysters and sewage, and method b used all of the samples with negative data substituted with half of the limit of detection (LOD).

b

Correlation coefficients between rotavirus concentrations in sewage and oysters and between the number of rotavirus-associated gastroenteritis cases and virus concentrations in oysters or sewage calculated by methods a and b at various time points. The time points are 1 to 7 weeks before (−1 to −7 weeks) or after (+1 to +7 weeks) the day of oyster collection. Statistically significant correlations (P < 0.05) are indicated by boldface values.