TABLE 2.
Effect of BAs upon vaginal Lactobacillus species d- and l-lactic acid production
| Biogenic amine | Lactic acid | Value(s) (mM) for: |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
L. crispatus VPI 3199 big |
L. crispatus VPI 3199 small |
L. gasseri NCTC 2948 |
L. iners AB107 |
L. jensenii 62G |
|||||||
| Positive control (n = 3) |
Treatment (n = 3) |
Positive control (n = 3) |
Treatment (n = 3) |
Positive control (n = 3) |
Treatment (n = 3) |
Positive control (n = 3) |
Treatment (n = 3) |
Positive control (n = 3) |
Treatment (n = 3) |
||
| 4,990 μM cadaverine | d-Lactic acid (avg) | 70.09 | 55.77 | 70.9 | 65.25 | 22.88 | 21.67 | NAc | NA | 126.29 | 123.56 |
| d-Lactic acid (SD) | 0.29 | 1.14 | 0.85 | 1.43 | 1.43 | 1.43 | NA | NA | 0 | 1.14 | |
| l-Lactic acid (avg) | 55.12a | 45.94a | 51.94 | 50.88 | 16.65 | 13.3 | 52.65a | 39.24a | 4.13 | 3.78 | |
| l-Lactic acid (SD) | 1.75 | 0.25 | 0.25 | 0.25 | 0.25 | 1.5 | 0.75 | 1.24 | 0 | 0 | |
| 3179 μM P,utrescine | d-Lactic acid (avg) | 58.19a | 50.92a | 63.23a | 52.56a | 67.88 | 56.98 | NA | NA | 60.05a | 58.99a |
| d-Lactic acid (SD) | 0.56 | 1.14 | 1.42 | 0.6 | 0 | 2.28 | NA | NA | 0.57 | 0.57 | |
| l-Lactic acid (avg) | 45.41 | 44 | 56 | 46.82 | 48.94 | 47.705 | 47.88 | 46.46 | 3.77 | 3.77 | |
| l-Lactic acid (SD) | 0.5 | 2.5 | 1.99 | 1 | 0.5 | 0.25 | 0.5 | 0.25 | 1 | 0.5 | |
| 59 μM spermidine | d-Lactic acid (avg) | 61.02 | 50.52 | 32.23 | 27.12 | 13.26 | 14.2 | NA | NA | 97.47 | 81.06 |
| d-Lactic acid (SD) | 4.58 | 0.4 | 1.42 | 4.55 | 0.46 | 0.81 | NA | NA | 11.66 | 7.49 | |
| l-Lactic acid (avg) | 40.43 | 37.77 | 30.47 | 25.65 | 8.95 | 11.19 | 40.59 | 39.06 | 4.48 | 4.01 | |
| l-Lactic acid (SD) | 8.82 | 1.78 | 2.04 | 3.58 | 0.41 | 1.41 | 1.24 | 2.2 | 0.35 | 0.2 | |
| 186 μM spermine | d-Lactic acid (avg) | 47.7a | 51.57a | 49.99 | 49.31 | 53.52 | 51.48 | NA | NA | 65.72a | 54.69a |
| d-Lactic acid (SD) | 1.06 | 0.93 | 3.24 | 0.4 | 2.94 | 1.53 | NA | NA | 3.75 | 3.43 | |
| l-Lactic acid (avg) | 42 | 38.83 | 44.94a | 50.12a | 33.53 | 33.89 | 42 | 39.41 | 2.25 | 2.36 | |
| l-Lactic acid (SD) | 1.08 | 4.48 | 0.89 | 1.13 | 1.74 | 2.07 | 4.79 | 0 | 0.2 | 0.35 | |
| 813 μM tyramine | d-Lactic acid (avg) | 103.79a | 91.01a | 91.95a | 29.54a | 29.81a | 16.09a | NA | NA | 139.03a | 162.34a |
| d-Lactic acid (SD) | 4.96 | 2.22 | 1.82 | 12.94 | 2.22 | 2.03 | NA | NA | 10.84 | 6.69 | |
| l-Lactic acid (avg) | 85.17 | 78.82 | 70.11 | 38.33 | 23.3b | 17.65b | 59.06b | 43.53b | 7.89 | 10.6 | |
| l-Lactic acid (SD) | 5.47 | 2.7 | 4.07 | 11.8 | 1.81 | 1.02 | 1.94 | 1.81 | 0.2 | 1.81 | |
a
Treatment and control were significantly different; P < 0.05.
b
Treatment and control were significantly different; q value, <0.05.
c
NA, not applicable (L. iners does not produce d-lactic acid).