Table 1. Clinically Relevant Mutations in the S Gene and Corresponding Results in Patients 1 and 2.*.
| Mutation | Patient 1 | Patient 2 |
|---|---|---|
| 69/70 deletion | Not detected | Not detected |
| D80A | Not detected | Not detected |
| T95I | Detected | Detected |
| D138Y | Not detected | Not detected |
| del142–145 | Detected (del144) | Detected (G142V, del144) |
| R190T | Not detected | Detected |
| D215G | Not detected | Not detected |
| F220I | Not detected | Detected |
| R237K | Not detected | Detected |
| Δ242–244 | Not detected | Not detected |
| R246T | Not detected | Detected |
| D253G | Not detected | Not detected |
| K417T | Not detected | Undetermined |
| L452R | Not detected | Undetermined |
| S477N | Not detected | P/H† |
| E484K | Detected | Undetermined |
| N501Y | Not detected | Undetermined |
| A570D | Detected | Not detected |
| D614G | Detected | Detected |
| H655Y | Not detected | Not detected |
| P681H | Detected | P/H† |
| A701V | Not detected | Undetermined |
| D796H | Detected | Undetermined |
*
These mutations are defined by the Centers for Disease Control and Prevention.6
†
P/H indicates partial heterozygosity (sequences from both the variant strain and the original strain first identified in Wuhan, China, were detected).