Table 4.
Hormone | Baseline | Treatment | Effect | P value | |
Total GLP-1 | Fasting value (pmol/L) |
9 (4,16) | 11 (5, 34) | 0 (−5, 30) | 0.345 |
AUC (h×pmol/L) |
67 (28, 90) | 71 (46, 117) | 20 (−20, 31) | 0.063 | |
Intact GLP-2 | Fasting value (pmol/L) |
15 (9, 22) | 16 (10, 53) | 1 (−2, 32) | 0.201 |
AUC (h×pmol/L) |
75 (47, 103) | 125 (89, 184) | 49 (39, 105) | 0.018 | |
Total PYY | Fasting value (pmol/L) |
25 (6, 83) | 25 (6, 85) | 0 (−56, 19) | 0.686 |
AUC (h×pmol/L) |
212 (30, 432) | 146 (70, 293) | 25 (−227, 79) | 0.612 | |
Total GIP | Fasting value (pmol/L) |
5 (1, 8) | 3 (1, 6) | −2 (−4, 4) | 0.288 |
AUC (h×pmol/L) |
158 (17, 204) | 99 (28, 190) | −44 (61, 37) | 0.091 | |
Glucagon | Fasting value (pmol/L) |
7 (3, 12) | 6 (2, 15) | −1 (−7, 7) | 0.389 |
AUC (h×pmol/L) |
29 (16, 46) | 25 (18, 33) | −1 (−17, 4) | 0.398 |
Data are presented as median (min, max).
AUC, area under the curve; GIP, glucose-dependent insulinotropic peptide; GLP, glucagon like peptide; PYY, peptide YY.