Comparison of mean of mean peak heights per channel (indicative of channel SNR) and mean number of detected waveforms per two-minute trial averaged across 16 channels and 81 trials taken in a total of 7 rats (trials not evenly distributed between individuals). Virtual referencing (VR), scaled virtual referencing (SVR), adaptive virtual referencing (AVR), and zero-phase component analysis whitening (ZCA) all offered statistically significant improvements over the baseline recording results (ANOVA followed by Tukey’s HSD with alpha = 0.05). AVR provided the best result, although statistical significance compared with other methods (VR, SVR, ZCA) was not reached.