Table 4.

Effect of treatment (TRT), day, session (Quiet or Music), time of day (a.m. or p.m.), and all relevant interactions on activity variables collected via Vetrax® activity sensors (AgLogica Technology, Norcross, GA) at 1,000–1,200 h (a.m.) and 1,330–1,530 h (p.m.) each day.

	Treatment				P-value
Variablea	Control (CON)	1.8 mg CBD/kg BW/day (LOW)	4.5 mg CBD/kg BW/day (HIGH)	SEb	CON vs. CBD	LOW vs. HIGH	Time of day	Session	Session*time	TRT*time	TRT*session	Day
Activity points	2,884	2,509	2,308	148.6	0.152	0.550	<0.001	0.055	0.014	0.287	0.465	<0.001
Activity (min)	1.23	0.87	0.85	0.144	0.204	0.937	<0.001	0.002	0.076	0.079	0.257	<0.001
No activity (h)	1.21	1.25	1.34	0.059	0.273	0.327	<0.001	0.014	<0.001	0.013	0.443	0.002
Resting (h)	0.71	0.70	0.62	0.050	0.384	0.234	<0.001	0.045	<0.001	0.006	0.203	0.002
Running (min)	0.04	0.03	0.04	0.006	0.602	0.544	<0.001	0.098	0.078	0.369	0.834	0.223
Walking (min)	1.29	0.87	0.82	0.148	0.138	0.857	<0.001	<0.001	0.084	0.060	0.217	<0.001
Scratching (s)	4.18	2.29	2.62	0.413	0.030	0.612	<0.001	0.930	0.274	0.326	0.886	0.730
Head shaking (s)	1.78	1.65	1.82	0.128	0.882	0.600	<0.001	0.926	0.305	0.319	0.212	0.375

Treatment effects are shown as the contrast between control (CON) and both CBD treatments (CBD) and the contrast between CBD treatments (LOW vs. HIGH).

^aExcept for No Activity and Resting, variables were not normally distributed and were transformed for statistical analysis. Data were back-transformed for reporting purposes. There was no effect of the treatment by day or the session by time by treatment interactions on any variable (P > 0.05) and thus are not shown.

^bStandard error (SE) of the back-transformed data was calculated as follows: SE = (back-transformed upper limit – back-transformed lower limit)/3.92.