Table 4. Evaluation of miRNA-target interaction filtering steps for the computed miRNA-target interactions based on miRNA-protein expression anticorrelation.

Step	# of Interactions	Interaction Phase	Gene Phase
ALL	8,193,904	38,505/33,243 ≈ 1.2	95/106 ≈ 0.9
ALL40	3,285,523	2,720/2,688 ≈ 1.0	107/91 ≈ 1.2
CORR	535,284	751/370 ≈ 2.0	115/50 ≈ 2.3
CORR+ABUN	165,937	719/352 ≈ 2.0	114/47 ≈ 2.4

Interaction phase shows the anticorrelated expressions of miRNA-protein target pairs with respect to positively correlated pairs. Gene phase shows the anticorrelated expression of target with average of all miRNA regulators with respect to the one having positive correlation. (Ratio is expected to be more than 1 to have anticorrelation tendency. Higher is better). See Table 1’s caption for the definition of row labels.