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. 2021 May 13;21:161. doi: 10.1186/s12890-021-01527-1

Table 4.

Sensitivity, specificity, and Youden index for assessed methods of ventilator-associated pneumonia diagnosis compared to the HELICS criteria as the reference standard

Criteria Ventilator-Associate Pneumonia % Sensitivity % Specificity Youden index a
Positive Negative Total
CDC/NHSN
Positive 45 38 83 54.22 100 0.542
Negative 0 2 2
Total 45 40 85
CPIS
Positive 44 20 64 68.75 95.23 0.640
Negative 1 20 21
Total 45 40 85
Johanson
Positive 44 21 65 67.69 95 0.627
Negative 1 19 20
Total 45 40 85

CDC/NHSN = centers for disease control and prevention national health safety network; CPIS = Clinical Pulmonary Infection Score, HELICS = Hospital in Europe Link for Infection Control through Surveillance

aA measure of the maximum diagnostic accuracy, where 1 signifies a perfect test and 0 signifies no diagnostic value