Table 4.

Stability study of ETM-ILE (mean ± SD, n = 3).

	Initial	Long-term stability test			Accelerated stability test
		3 m	6 m	12 m	3 m	6 m	12 m
Size (nm)	168.0 ± 0.3	166.9 ± 1.7	170.2 ± 2.2	170.8 ± 2.6	168.9 ± 2.8	168.0 ± 1.5	170.4 ± 2.7
PDI	0.108 ± 0.028	0.112 ± 0.004	0.105 ± 0.009	0.109 ± 0.021	0.100 ± 0.014	0.111 ± 0.013	0.115 ± 0.012
pH	7.63 ± 0.07	7.56 ± 0.05	7.61 ± 0.02	7.60 ± 0.03	7.59 ± 0.04	7.57 ± 0.03	7.52 ± 0.04
ZP (mV)	−36.4 ± 0.2	−36.9 ± 0.3	−36.5 ± 0.5	−37.2 ± 0.9	−35.9 ± 0.8	−36.7 ± 0.4	−36.2 ± 0.6
DL (mg/mL)	2.00 ± 0.01	2.00 ± 0.02	2.00 ± 0.03	2.00 ± 0.04	2.00 ± 0.04	2.00 ± 0.04	1.97 ± 0.07
EE (%)	97.65 ± 0.16	97.66 ± 0.46	97.50 ± 0.35	97.33 ± 0.76	97.43 ± 0.26	97.53 ± 0.43	97.17 ± 0.35