Fig 4.

RAW 264.7 cells’ viability following 24 h of exposure to the crude extracts obtained from endophytic fungi associated with Halopteris scoparia (10–200 μg/ mL) and expressed as % of the control (A). Nitric oxide (NO) production induced on RAW 264.7 cells by fungal extracts at non-toxic concentrations after 24 h of treatment (B). Nitric oxide (NO) production induced on RAW 264.7 cells by fungal extracts at non-toxic concentrations and 1 μg/mL of LPS (C). The fungi from which the extracts were obtained are abbreviated as follows: Asp.che13 or 20, isolates 13 or 20 of Aspergillus chevalieri; Pen.siz, Penicillium sizovae; Pen.exi, Penicillium sect. Exilicaulis; Diap.sp, Diaporthe sp.; Nig.ory2 or 89, isolates 2 or 89 of Nigrospora oryzae; Fus.i-e, Fusarium incarnatum-equiseti complex; Art.aru, Arthrinium arundinis; Ste.gra, Stemphylium gracilariae. The values correspond to mean ± SEM. * and ^# represent significant differences (One-way ANOVA, Dunnett’s test; p< 0.05) when compared with the vehicle and LPS, respectively.