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. 2021 May 13;16(5):e0250954. doi: 10.1371/journal.pone.0250954

Table 3. Concentration of the fungal crude extracts that causes 50% inhibition of an enzymatic reaction (IC50).

Fungal producers Hyaluronidase (μg/mL) Collagenase (μg/mL) Elastase (μg/mL) Tyrosinase (μg/mL)
Aspergillus chevalieri (isolate 13) >200 65.6 (79.7–115.5) >200 >200
Aspergillus chevalieri (isolate 20) >200 51.7 (37.8–69.7) 56.1 (48.5–64.5) >200
Penicillium sizovae >200 >200 >200 >200
Penicillium sect. Exilicaulis 99.1 (87.3–112.6) 107.0 (74.0–116.9) >200 >200
Diaporthe sp. >200 98.6 (86.7–120.2) >200 39.8 (32.2–49.1)
Nigrospora oryzae (taxon 2) >200 >200 >200 >200
Nigrospora oryzae (taxon 89) >200 >200 >200 >200
Fusarium incarnatum-equiseti complex >200 >200 >200 >200
Arthrinium arundinis >200 >200 >200 >200
Stemphylium gracilariae >200 112.3 (90.6–142.0) >200 >200
EGCG 119.1 (126.1–320.4) 4.8 (4.1–5.5) 113.9 (80.7–160.0) -
Kojic acid - - - 18.3 (14.0–23.9)