Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 11;28(1):920–929. doi: 10.1080/10717544.2021.1914777

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 1. — Interaction between HA and CD44v6 increased chemotherapy resistance in colorectal cancer cells. (A,B) Expression of CD44v6 in the indicated cells (***p < .001, compared with NCM460 cells). (C) Expression of HA in the indicated cells (***p < .001, compared with NCM460 cells). (D) Cytotoxicity of oxaliplatin in the indicated cells. RKO cells were more resistant to oxaliplatin than HT-29 cells. (E) RKO cells were treated with 0.05 mM 4MU or 0.05 mM 4MU + 10 μM Oxa for 72 h. DMSO was used as the vehicle control. The 4-MU can sensitize RKO cells to Oxa (**p < .01). All results are expressed as the mean ± SD of three independent experiments.