Table 2. Multivariable analysis of BMI groups in African Americans.
CHR | Genes | SNP | Minor Allele | MAF | Adjusted OR* | SE | L95 | U95 | P-Value |
---|---|---|---|---|---|---|---|---|---|
1 | APOA2 | rs50820000 | G | 0.245388 | 1.27 | 0.15 | 0.95 | 1.70 | 0.10 |
1 | APOA2 | rs50850000 | G | 0.093461 | 0.89 | 0.22 | 0.58 | 1.36 | 0.59 |
1 | LEPR | rs11371010 | A | 0.479325 | 1.01 | 0.13 | 0.77 | 1.30 | 0.97 |
1 | APOA2 | rs64134530 | A | 0.024297 | 0.74 | 0.43 | 0.32 | 1.72 | 0.49 |
3 | KNG1 | rs11924390 | C | 0.492602 | 1.24 | 0.12 | 0.97 | 1.59 | 0.08 |
3 | KNG1 | rs18516650 | G | 0.438151 | 1.27 | 0.12 | 0.99 | 1.64 | 0.06 |
3 | ADIPOQ | rs64441750 | A | 0.314015 | 1.10 | 0.14 | 0.84 | 1.46 | 0.45 |
3 | CDH13 | rs86426500 | T | 0.151891 | 1.23 | 0.18 | 0.86 | 1.76 | 0.26 |
5 | ADIPOQ | rs43113940 | G | 0.301842 | 1.01 | 0.14 | 0.77 | 1.33 | 0.93 |
7 | Leptin | rs77990390 | A | 0.091181 | 1.21 | 0.30 | 0.77 | 1.91 | 0.40 |
11 | TUB | rs15281330 | G | 0.147654 | 1.00 | 0.18 | 0.69 | 1.44 | 1.00 |
11 | TUB | rs22723830 | A | 0.129245 | 1.25 | 0.19 | 0.86 | 1.80 | 0.24 |
11 | APOA5 | rs66279900 | G | 0.123607 | 0.81 | 0.19 | 0.56 | 1.20 | 0.30 |
15 | SCG3 | rs16964465 | C | 0.180158 | 1.20 | 0.16 | 0.88 | 1.67 | 0.25 |
15 | SCG3 | rs16964476 | G | 0.182862 | 1.17 | 0.16 | 0.84 | 1.63 | 0.35 |
15 | SCG3 | rs37642200 | G | 0.176916 | 1.23 | 0.17 | 0.89 | 1.71 | 0.21 |
16 | FTO | rs11219800 | A | 0.471949 | 1.27 | 0.13 | 0.99 | 1.64 | 0.06 |
16 | CDH13 | rs38651880 | T | 0.381064 | 1.01 | 0.13 | 0.79 | 1.305 | 0.91 |
16 | ADIPOQ | rs71937880 | G | 0.1375 | 0.69 | 0.20 | 0.47 | 1.03 | 0.07 |
16 | FTO | rs11076023 | A | 0.334827 | 0.90 | 0.14 | 0.69 | 1.18 | 0.45 |
16 | FTO | rs14210850 | C | 0.084113 | 1.452 | 0.23 | 0.91 | 2.30 | 0.11 |
16 | FTO | rs15589020 | A | 0.074835 | 1.25 | 0.24 | 0.77 | 2.01 | 0.37 |
16 | FTO | rs80501360 | A | 0.44015 | 1.40 | 0.13 | 1.08 | 1.80 | 0.01 |
18 | MC4R | rs22296160 | T | 0.022479 | 0.67 | 0.45 | 0.28 | 1.64 | 0.39 |
Abbreviations: CHR, chromosome; SNP, single nucleotide polymorphism; MAF, minor allele frequency; OR, odds ratio; SE, standard error.
* Adjusted for sex and age.