TABLE 2.
Results of the stepwise multivariable Cox PH regression modeling LID onset vs non-genetic factors.
| Exposure | HR | CI (lower) | CI (upper) | z | p |
|---|---|---|---|---|---|
| Gender (women) | 1.39 | 1.05 | 1.82 | 2.33 | 0.02 |
| Familiarity | 1.24 | 0.95 | 1.63 | 1.55 | 0.12 |
| AAO | 0.98 | 0.97 | 1.00 | −2.33 | 0.02 |
| Hoehn and yahr | 0.89 | 0.77 | 1.04 | −1.43 | 0.15 |
| YOD | 0.94 | 0.92 | 0.97 | −3.80 | 1.4 × 10−4 |
Here we report only exposures which were retained in stepwise multivariable models. AAO, age at onset; CI (lower/upper), inferior and superior limits of the 95% Confidence Interval of HRs; HR, hazard ratio; p, p-value; YOD, years of disease; z, z-score. Significant associations surviving Bonferroni correction (p < 4.5 × 10−3) are highlighted in bold.