Table 1.
MicroRNAs as potential biomarkers for colorectal cancer.
| MicroRNA | Expression | Sample | Biomarker | Reference |
|---|---|---|---|---|
| miR-21 | ↑ | Tissue/Plasma exosomes | Diagnostic/Prognostic | (1–4) |
| miR-23a | ↑ | Serum/Plasma exosomes | Diagnostic | (3, 5) |
| miR-17-5p | ↑ | Plasma/Tissue/Exosomes | Diagnostic/Prognostic | (6, 7) |
| miR-150-5p | ↓ | Serum | Diagnostic | (8, 9) |
| miR-92a | ↑ | Plasma exosomes | Diagnostic | (3, 4) |
| miR-29a | ↑ | Serum/Exosomes/Stool | Diagnostic | (4, 10) |
| miR-122 | ↑ | Serum | Diagnostic/Prognostic | (11) |
| miR-199a/b-3p | ↑ | Serum | Prognostic | (12) |
| miR-199a-5p | ↑ | Serum | Prognostic | (12) |
| miR-199b-5p | ↑ | Serum | Prognostic | (12) |
| miR-99b-5p | ↓ | Serum | Diagnostic | (8) |
| miR-4461 | ↓ | Serum | Diagnostic/Therapeutic | (13) |
| miR-92b | ↓ | Serum | Diagnostic | (14) |
| miR‐320d | ↑ | Serum | Diagnostic | (15) |
| miR-301a | ↑ | Serum | Diagnostic | (5) |
| miR-181a-5p | ↑ | Plasma/Tissue/Exosomes | Diagnostic | (6) |
| miR-18a-5p | ↑ | Plasma/Tissue/Exosomes | Diagnostic | (6) |
| miR-18b-5p | ↑ | Plasma/Tissue/Exosomes | Diagnostic | (6) |
| miR-548c-5p | ↓ | Plasma exosomes | Diagnostic/Prognostic | (16) |
| miR-27a | ↑ | Plasma exosomes | Diagnostic/Prognostic | (17) |
| miR-130a | ↑ | Plasma exosomes | Diagnostic/Prognostic | (17) |
| miR-92a-3p | ↑ | Plasma exosomes | Prognostic | (7) |
| miR-6803-5p | ↑ | Plasma exosomes | Diagnostic/Prognostic | (18) |
| miR-6869-5p | ↓ | Plasma exosomes | Prognostic | (19) |
| miR-125a-3p | ↑ | Plasma exosomes | Diagnostic | (20) |
| miR-96-5p | ↓ | Tissue/Plasma exosomes | Diagnostic/Therapeutic | (21) |
| miR-149 | ↓ | Tissue/Plasma exosomes | Diagnostic/Therapeutic | (21) |
| miR-19a-3p | ↑ | Tissue/Plasma exosomes | Diagnostic | (22) |
| miR-21-5p | ↑ | Tissue/Plasma exosomes | Diagnostic | (22) |
| miR-425-5p | ↑ | Tissue/Plasma exosomes | Diagnostic | (22) |
| miR-1246 | ↑ | Plasma exosomes | Diagnostic | (3) |
| miR-4772-3p | ↓ | Plasma exosomes | Prognostic | (23) |
| miR-19a | ↑ | Serum/Exosomes | Prognostic | (24) |
| miR-34a-5p | ↓ | Tissue | Prognostic | (25) |
| miR-132 | ↓ | Tissue | Prognostic | (26) |
| miR-199b | ↓ | Tissue | Prognostic | (27) |
| miR-145 | ↓ | Tissue/Serum | Prognostic | (1) |
| miR-223 | ↓ | Stool | Diagnostic | (10) |
| miR-224 | ↓ | Stool | Diagnostic | (10) |
| miR-195-5p | ↓ | Tissue/Cell lines | Prognostic | (28) |
| miR-145-5p | ↓ | Tissue | Diagnostic/Therapeutic | (29) |
References showed in Supplementary Material 1 .