Table 2.
Potential long non-coding RNAs as biomarkers for the diagnosis and prognosis of colorectal cancer.
| LncRNA | Expression | Sample | Biomarker | Reference |
|---|---|---|---|---|
| CCAT1 | ↑ | Tissue/Plasma | Diagnostic/Prognostic | (1–4) |
| HOTAIR | ↑ | Tissue/Cell lines | Diagnostic/Therapeutic | (5–7) |
| NEAT1 | ↑ | Cell lines | Diagnostic/Therapeutic | (8–10) |
| PVT1 | ↑ | Tissue | Diagnostic/Prognostic | (11–13) |
| MALAT1 | ↑ | Tissue/Cell lines | (3, 14) | |
| UAC1 | ↑ | Tissue/Cell lines/Exosomes | Diagnostic/Prognostic | (11, 15) |
| BCYRN1 | ↑ | Tissue/Cell lines | Prognostic/Therapeutic | (16, 17) |
| CCAT2 | ↑ | Tissue | Diagnostic/Prognostic | (1, 18) |
| XIST | ↑ | Tissue/Cell lines | Prognostic/Therapeutic | (19, 20) |
| PANDAR | ↑ | Tissue/Cell lines | Prognostic | (21, 22) |
| H19 | ↑ | Tissue/Cell lines | Diagnostic/Prognostic/Therapeutic | (23, 24) |
| SNHG6 | ↑ | Tissue/Cell lines | Prognostic/Therapeutic | (25, 26) |
| LINC01510 | ↑ | Tissue/Cell lines | Prognostic | (27, 28) |
| MIR4435-2HG | ↑ | Tissue | Diagnostic/Prognostic | (29, 30) |
| SLCO4A1-AS1 | ↑ | Tissue/Cell lines | Prognostic/Therapeutic | (31, 32) |
| RP11-59H7.3 | ↑ | Tissue/Serum/Cell lines | Diagnostic/Therapeutic | (33) |
| GACAT3 | ↑ | Tissue | Diagnostic/Prognostic | (34) |
| LINC00152 | ↑ | Tissue | Diagnostic/Prognostic | (34) |
| TRERNA1 | ↑ | Tissue/Cell lines | Prognostic | (35) |
| LEF1-AS1 | ↑ | Tissue/Cell lines | Therapeutic/Prognostic | (36) |
| B3GALT5-AS1 | ↓ | Serum | Diagnostic | (37) |
| DANCR | ↑ | Serum | Diagnostic | (38) |
| HANR | ↑ | Tissue | Diagnostic/Prognostic | (39) |
| MFI2-AS1 | ↑ | Tissue | Prognostic/Therapeutic | (40) |
| treRNA | ↑ | Tissue | Prognostic | (41) |
| LINC00461 | ↑ | Tissue/Cell lines | Prognostic/Therapeutic | (42) |
| AP003555.2 | ↑ | Tissue | Prognostic | (43) |
| AP006284.1 | ↑ | Tissue | Prognostic | (43) |
| LINC01602 | ↑ | Tissue | Prognostic | (43) |
| LINRIS | ↑ | Tissue/Cell lines | Prognostic/Therapeutic | (44) |
| cCSC1 | ↑ | Tissue/Cell lines | Prognostic/Therapeutic | (45) |
| LINC01234 | ↑ | Tissue | Prognostic | (46) |
| SNHG11 | ↑ | Plasma | Diagnostic/Prognostic | (47) |
| AK001058 | ↑ | Cell lines | Diagnostic/Therapeutic | (48) |
| DNAH17-AS1 | ↑ | Tissue | Prognostic/Therapeutic | (49) |
| RP11-400N13.2 | ↑ | Tissue | Prognostic/Therapeutic | (49) |
| LINC00957 | ↑ | Tissue/Cell lines | Prognostic/Therapeutic | (50) |
| NKILA | ↓ | Tissue/Cell lines | Diagnostic/Prognostic | (51) |
| MEG3 | ↓ | Tissue/Cell lines/Serum | Diagnostic/Prognostic | (52) |
| XIRP2-AS1 | ↓ | Tissue/Cell lines | Prognostic/Therapeutic | (53) |
| CTA-941F9.9 | ↓ | Tissue | Diagnostic | (54) |
| ZFAS1 | ↑ | Tissue/Cell lines | Diagnostic/Therapeutic | (55) |
| LNRRIL6 | ↑ | Tissue/Cell lines | Prognostic/Therapeutic | (56) |
| KIAA0125 | ↓ | Tissue/Cell lines | Diagnostic | (57) |
| IQCJ-SCHIP1 | ↓ | Tissue | Prognostic/Therapeutic | (58) |
| DILC | ↓ | Tissue | Diagnostic/Prognostic | (59) |
| CRCAL-3 | ↑ | Tissue/Cell lines | Diagnostic/Prognostic/Therapeutic | (60) |
| CASC19 | ↑ | Tissue/Cell lines | Diagnostic/Therapeutic | (61) |
| HOTTIP | ↑ | Tissue | Diagnostic | (11) |
| PVT1 | ↑ | Tissue | Diagnostic | (11) |
| UCA1 | ↑ | Tissue | Diagnostic | (11) |
| RP11 | ↑ | Tissue | Therapeutic | (62) |
| KAT7 | ↓ | Tissue/Cell lines | Diagnostic/Therapeutic | (63) |
| TINCR | ↑ | Tissue/Cell lines | Diagnostic/Prognostic | (64) |
| GIHCG | ↑ | Tissue/Cell lines | Prognostic/Therapeutic | (65) |
| LUCAT1 | ↑ | Tissue/Cell lines | Prognostic/Therapeutic | (66) |
| ENST00000547547 | ↓ | Tissue/Cell lines | Prognostic/Diagnostic | (67) |
| MLK7–AS1 | ↑ | Tissue/Cell lines | Diagnostic/Therapeutic | (68) |
| MAPKAPK5-AS1 | ↑ | Tissue/Cell lines | Prognostic/Therapeutic | (69) |
| SNHG15 | ↑ | Tissue | Prognostic | (70) |
| RP1–85F18.6 | ↑ | Tissue/Cell lines | Diagnostic/Prognostic | (71) |
| NONHSAT074176.2 | ↓ | Tissue | Diagnostic/Therapeutic | (72) |
| DLEU1 | ↑ | Tissue/Cell lines | Therapeutic | (73) |
| CYTOR | ↑ | Tissue | Prognostic/Therapeutic | (74) |
| SPINT1-AS1 | ↑ | Tissue/Serum exosomes | Prognostic/Therapeutic | (75) |
| u50535 | ↑ | Tissue/Cell lines | Diagnostic/Prognostic | (76) |
| RP11-909B2.1 | ↓ | Tissue/Cell lines | Diagnostic/Prognostic | (77) |
| AK098783 | ↑ | Tissue | Prognostic | (78) |
| XLOC_010588 | ↑ | Tissue/Cell lines | Diagnostic/Prognostic/Therapeutic | (79) |
| 91H | ↑ | Serum exosomes | Diagnostic/Prognostic/Therapeutic | (80) |
| SNHG1 | ↑ | Tissue/Cell lines | Diagnostic/Therapeutic | (81) |
| LINC00959 | ↓ | Tissue/Cell lines | Prognostic | (82) |
| GHRLOS | ↓ | Tissue | Prognostic/Therapeutic | (83) |
| CPS1-IT1 | ↓ | Tissue/Cell lines | Prognostic/Therapeutic | (84) |
| HNF1A-AS1 | ↑ | Tissue/Cell lines | Prognostic/Therapeutic | (85) |
| HOXA-AS2 | ↑ | Tissue/Cell lines | Diagnostic/Therapeutic | (86) |
| HEIH | ↑ | Tissue/Cell lines | Prognostic/Therapeutic | (87) |
| NONHSAT062994 | ↓ | Tissue/Cell lines | Prognostic/Therapeutic | (88) |
| BANCR | ↑ | Tissue | Prognostic | (89) |
| LL22NC03-N64E9.1 | ↑ | Tissue/Cell lines | Prognostic/Therapeutic | (90) |
| ZEB1-AS1 | ↑ | Tissue/Cell lines | Prognostic | (20) |
| BCAT1 | ↓ | Tissue/Cell lines | Prognostic | (91) |
| BLACAT1 | ↑ | Tissue/Cell lines | Diagnostic/Therapeutic | (92) |
| UBC1 | ↑ | Tissue/Cell lines | Diagnostic | (93) |
| SNHG12 | ↑ | Tissue/Cell lines | Diagnostic/Prognostic | (94) |
| SPRY4-IT1 | ↑ | Tissue | Prognostic | (95) |
| HOXA11-AS | ↓ | Tissue/Cell lines | Prognostic/Therapeutic | (96) |
| CRNDE-h | ↑ | Serum exosomes | Diagnostic/Prognostic | (97) |
| Loc554202 | ↓ | Tissue | Prognostic | (98) |
| FOXP4-AS1 | ↑ | Tissue/Cell lines | Prognostic/Therapeutic | (99) |
| HOTAIRM1 | ↓ | Tissue/Cell lines | Diagnostic | (100) |
| CTNNAP1 | ↓ | Tissue | Diagnostic | (101) |
| LINC01133 | ↓ | Tissue/Cell lines | Prognostic/Therapeutic | (102) |
| CASC11 | ↑ | Tissue/Cell lines | Diagnostic/Therapeutic | (103) |
| TUG1 | ↑ | Tissue/Cell lines | Diagnostic/Prognostic/Therapeutic | (104) |
| PRNCR1 | ↑ | Tissue/Cell lines | Diagnostic | (105) |
| ATB | ↑ | Plasma | Diagnostic/Prognostic | (2) |
References showed in Supplementary Material 2 .