Table 3. Laboratory characteristics of the ten patients diagnosed with Hansen disease relapse.
| First diagnosis–Bacterial load | Surveillance | Relapse–Bacterial load | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BI | LBI | Number of years until BI~0 | Lowest BI | Years from RFT to relapse | BI | LBI | |||||
| Before MDT | End MDT | Before MDT | End MDT | Before MDT | End MDT | Before MDT | Observations | ||||
| 1 | 4.16 | 3.83 | 4.85 | 2.00 | 4.1 | 0.75 | 5.4 | 1.25 | 0.75 | NE | ENL at 11th dose |
| 2 | 4.00 | 1.00 | 3.50 | NA | 3.5 | 0.00 | 5.6 | 0.50 | 0.00 | 0.00 | RR at 12th dose |
| 3 | 4.00 | 3.66 | 5.85 | 2.30 | 2.1 | 0.00 | 11.6 | 2.50 | 2.00 | 4.50 | no reaction |
| 4 | 4.00 | 3.66 | 4.80 | 3.60 | 6.9 | 0.50 | 13.2 | 2.25 | NA | 3.50 | ENL at diagnosis |
| 5 | 3.83 | 3.75 | 5.80 | 3.50 | 7.3 | 0.00 | 8.1 | 0.25 | 3.75 | 5.85 | no reaction |
| 6 | 2.83 | 3.66 | 3.60 | 2.30 | 8.6 | 0.00 | 9.4 | 0.50 | 0.00 | 1.60 | neuritis at 11th dose |
| 7 | 2.16 | 2.83 | 4.50 | 2.50 | 6.4 | 0.00 | 14.9 | 5.00 | 4.00 | 3.50 | EM at 1st dose |
| 8 | 4.00 | 4.16 | 3.50 | 3.50 | 9.2 | 0.00 | 10.5 | 2.50 | 0.00 | 4.50 | ENL at 1st dose |
| 9 | 3.00 | 3.·50 | 5.90 | 3.50 | * | 3.1 | 4.00 | 1.75 | 3.85 | ENL at 2nd dose was treated w/minocycline + history of chronic alcoholism | |
| 10 | 4.00 | 2.75 | 4.6 | ND | 7.0 | 1 | 10.5 | 1.25 | 1 | 3.5 | Insulin-dependent diabetes, ENL during first treatment. |
BI = baciloscopic index, LBI = logarithmic biopsy index, MDT = multidrug therapy, DG = disability grade, ENL = erythema nodosum leprosum, RR = reversal reaction, EM = erythema multiforme, NA = not available, NE = not evaluated because there was no skin lesion.
*lowest BI was 3.50 at 1.7 years after RFT, and maintained 4.0 thereafter