Table 4:
Correlations between biomarkers and episodic memory
| RAVLT Learning* |
RAVLT 30 Minutes’ Recall |
|||
|---|---|---|---|---|
| R |
R |
|||
| S1 | S2 | S1 | S2 | |
| Hippocampus | .49§ | .70†‡ | .35 | .71†‡ |
| A: Middle temporal LH | .51† | .38 | .33 | .22 |
| B: Inferior parietal LH | .67† | .44§ | .48‡ | .53† |
| C: Entorhinal LH | .66† | .64†‡ | .46 | .64†‡ |
| D: Precuneus (toward isthmus) LH | .50† | .48† | .15 | .44† |
| E: Superior frontal LH | .43 | .42 | .24 | .38 |
| A: Middle temporal RH | .49§ | .34 | .16 | .39† |
| B: Inferior parietal RH | .56† | .49† | .53† | .60† |
| C: Entorhinal RH | .35 | .50† | .23 | .53† |
| D: Precuneus (toward isthmus) RH | .28 | .54† | .04 | .54† |
| E: Superior frontal RH | .38 | .36 | .29 | .22 |
| Tau | −.28 | −.60† | −.09 | −.73†‡ |
| Aβ42 | .09 | .42 | .33 | .35 |
| APOE | −.09 | −.17 | −.34 | −.18 |
Note:—S1 indicates Sample 1; S2, Sample 2; RAVLT, Rey Auditory-Verbal Test; APOE, apolipoprotein E; Aβ42; amyloid beta 42 peptide; LH, left hemisphere; RH, right hemisphere; R, Pearson r.
*
RAVLT learning is the sum of correct responses across learning trials 1 to 5. APOE is quantified as the number of ε4 alleles (0, 1, or 2). For tau, cutoff criteria are used in the analyses (0 for nonpathologic, 1 for pathologic), whereas for Aβ42 the actual values are used because only 2 participants in Sample 1 had pathologic values.
†
P < .05.
‡
P < .05 when the effect of age is controlled for.
§
P < .06.