Table 3:

Approved pharmacologic agents for treatment of osteoporosis

Drug (Brand names)	Dose†	Proven Fracture Reduction*	Indication
Alendronate (Fosamax)	10 mg daily, 70 mg weekly	Vertebral, hip, nonvertebral	Postmenopausal women, men; glucocorticoid-induced osteoporosis
Risedronate (Actonel)	5 mg daily, 35 mg weekly, 75 mg 2 days/month	Vertebral, hip, nonvertebral	Postmenopausal women, men; glucocorticoid-induced osteoporosis
Ibandronate (Boniva)	2.5 mg daily, 150 mg monthly, 3 mg IV every 3 months	Vertebral, nonvertebral	Postmenopausal women
Zoledronic acid (Reclast, Zometa)	5 mg IV yearly	Vertebral, hip, nonvertebral	Postmenopausal women
Raloxifene (Evista)	60 mg daily	Vertebral	Postmenopausal women
Salmon calcitonin (Miacalcin, Fortical)	200 U intranasally daily	Vertebral	Postmenopausal women
Teriparatide (Forteo)	20 mcg subcutaneously daily for ≤2 years	Vertebral, nonvertebral	Postmenopausal women

Note:—IV indicates intravenous.

^*In postmenopausal women with osteoporosis.

^†Oral unless otherwise noted.