Table 2:

Multivariate analysis of specific prognostic factors

Prognostic Factor	Hazard Ratio* (95% CI)	P Value
Age ≥50 years	NA	.814
Sex: male	2.632 (1.153–6.010)	.021
Histologic diagnosis of GBM	9.707 (3.163–29.788)	<.001
Neurologic function: home or hospital†	NA	.435
Abnormal mental status	NA	.228
KPS score ≤ 80	NA	.150
Extent of surgery: biopsy	2.692 (1.196–6.061)	.016
Tumor enhancement: present	NA	.726
rCBV > 2.3	4.739 (1.950–11.518)	<.001

Note:—NA indicates not applicable; GBM, glioblastoma multiforme; KPS, Karnofsky performance scale; rCBV, relative cerebral blood volume.

^*Hazard ratio was not calculated when P ≥ .05.

^†Neurologic function is limited so that the patient is either confined to the home or hospitalized.