Fig 2.

Leukemic hemorrhage. This 6-month-old boy presented with fever, leukocytosis thrombocytopenia, anemia, and hepatosplenomegaly. Axial FLAIR (A), T2-weighted (B), and SWI (C) images show a large hematoma in the left frontal lobe (asterisks). A few small hemorrhages with surrounding edema were also visible in the right subcortical white matter (open arrows) on the FLAIR and T2-weighted images. There is also a small right convexity subdural collection with hemorrhage (arrows). However, numerous additional hemorrhagic foci throughout the bilateral hemispheric white matter are only visible on SWI. He was subsequently diagnosed with acute lymphocytic leukemia. The multiple intracranial hemorrhages were thought to be associated with seizures that were difficult to control, with profound cognitive and motor impairments, and hydrocephalus that required ventriculoperitoneal shunting. Several years later, he remains profoundly impaired.